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Which is the most frequent clinical presentation of invasive group A streptococcal infection in children?

Which is the most frequent clinical presentation of invasive group A streptococcal infection in children?

Results: We enrolled 181 children, 7 days to 16 years of age. The principal site of invasive infection was blood (126 children, 69.6%), and the most frequent clinical presentation was pneumonia in 46 children (25.4%).

What are signs and symptoms of group A streptococcus?

Symptoms of group A streptococcal infection

  • a sore, red throat with thick pus-like fluid around the tonsils.
  • fever and chills.
  • enlarged and tender lymph nodes in and around the neck.
  • vomiting and abdominal complaints, particularly in children.

What is the most common infection in the oral cavity?

Overview. Members of the human herpesvirus (HHV) and human papillomavirus (HPV) families cause the most common primary viral infections of the oral cavity. HPV infections have received particular attention in recent years, as high-risk strains have been linked to some cases of oral squamous cell carcinoma.

What are the clinical presentations of group A streptococcal infection?

Strep throat has an incubation period of 2-4 days and is characterized by sudden onset of sore throat, cervical lymphadenopathy, malaise, fever, and headache. Younger patients may also develop nausea, vomiting, and abdominal pain. Acute sinusitis manifests as persistent coryza, postnasal drip, headache, and fever.

What lymphatic tissue is most commonly affected by Group A streptococcus?

Clinical importance of group A streptococcal diseases Group A Streptococcus (GAS) is a human-specific pathogen having high disease prevalence worldwide. The vast majority of GAS infections involve the epithelium of the throat or skin.

Is strep throat a systemic infection?

Symptoms. Group A strep infection symptoms depend on where the infection is. The common symptoms include pain in the affected area, redness, and swelling. If the infection progresses or is a systemic infection, such as scarlet fever or toxic shock syndrome, you would develop fever, muscle aches, and flu-like symptoms.

What is invasive group A streptococcal disease?

What is invasive group A streptococcal disease? Invasive GAS disease is a severe and sometimes life-threatening infection in which the bacteria have invaded parts of the body, such as the blood, deep muscle and fat tissue or the lungs.

How common is group A strep?

About 10-15% of people with other forms of invasive GAS disease die. How Common is Invasive Group A Streptococcal Disease? It is estimated that about 10,000-15,000 cases of invasive GAS disease occur in the U.S. each year resulting in over 2,000 deaths.