What is transformation of follicular lymphoma?

What is transformation of follicular lymphoma?

What is transformation? Transformation is when a slow-growing (low-grade) lymphoma changes into a faster-growing (high-grade) lymphoma. It is important to know if your lymphoma has transformed because transformed lymphoma needs different treatment to low-grade lymphoma. Most low-grade lymphomas never transform.

Is transformed follicular lymphoma curable?

If aggressive chemotherapy alone fails to induce remission, then second-line treatments that may be considered include radioimmunotherapy and high-dose chemotherapy followed by stem cell transplantation. There is no single treatment for all patients with transformed lymphoma.

What is the survival rate of follicular non Hodgkin’s lymphoma?

The overall 5-year relative survival rate for people with NHL is 73%. But it’s important to keep in mind that survival rates can vary widely for different types and stages of lymphoma….Follicular lymphoma.

SEER Stage 5-Year Relative Survival Rate
Regional 91%
Distant 86%
All SEER stages combined 90%

How do you treat transformed follicular lymphoma?

High Dose Chemotherapy Treatment for Transformed NHL. ​Patients with transformed lymphomas may achieve a significantly higher rate of long-term survival when treated with high-dose therapy and stem cell transplantation, according to an early study published in the Journal of Clinical Oncology.

Can follicular lymphoma become aggressive?

There is a risk in individuals with follicular lymphoma that the cancer can go under a transformation from a slow-growing (indolent) form into a more aggressive form called diffuse large B-cell lymphoma (DLBCL). As many as 30-40% of individuals may experience aggressive transformation of indolent follicular lymphoma.

Can follicular lymphoma turn into leukemia?

Follicular lymphoma transforming into acute lymphoblastic leukemia has been documented in a limited number of cases [2,3,11,12].

What is the longest someone has lived with follicular lymphoma?

The five-year survival rate for follicular lymphoma is between 80 and 90 percent, which means at least 80 to 90 percent of patients diagnosed with follicular lymphoma can live for at least five years after the diagnosis. Half of the patients diagnosed with this type of cancer can live for approximately 10 to 12 years.

What are the chances of follicular lymphoma returning?

Approximately 20% of patients with follicular lymphoma will relapse within 2 years of diagnosis. Although the optimal management of these patients has not been established, clinicians may be guided by data from recent clinical trials, according to Nathan H.

Can you live a long life with follicular lymphoma?

Follicular lymphoma is slow-growing cancer. People diagnosed with the disease may not find a cure but can still live for a long time with it. The five-year survival rate for follicular lymphoma is 80-90% with patients surviving for a median of 10-12 years.