What is the difference between a reciprocal translocation and a nonreciprocal translocation?
Nonreciprocal translocations are one-way translocations in which a chromosomal segment is transferred to a nonhomologous chromosome. Reciprocal translocations, on the other hand, involve the exchange of segments from two nonhomologous chromosomes.
What is reciprocal translocation?
Reciprocal translocations occur when part of one chromosome is exchanged with another. Translocations can disrupt functional parts of the genome and have implications for protein production with phenotypic consequences. Reciprocal translocations are usually balanced and so may not have apparent functional implications.
What is an example of reciprocal translocation?
A prototypical example of this phenomenon is represented by the Philadelphia chromosome associated with human lymphoma/leukemia. This specific chromosomal abnormality consists of a translocation between the long arms of chromosomes 9 and 22 and is seen in 85% of patients with chronic myelogenous leukemia.
What is the difference between reciprocal and nonreciprocal?
The main difference between reciprocal and nonreciprocal translocation is that reciprocal translocation is a two-way translocation responsible for the exchange of chromosomal segments between two nonhomologous chromosomes, whereas nonreciprocal translocation is a one-way translocation responsible for the movement of a …
What is difference between reciprocal and Robertsonian translocation?
In a reciprocal translocation, two different chromosomes have exchanged segments with each other. In a Robertsonian translocation, an entire chromosome attaches to another at the centromere.
What causes reciprocal translocation?
Reciprocal translocations occur due to the exchange of chromosome material between two nonhomologous chromosomes. When the amount of genetic material is balanced, there is no phenotypic effect on the individual because of a balanced complement of genes.
Is reciprocal translocation same as balanced translocation?
The ends of two chromosomes change places. On the right, a balanced translocation. This is called a reciprocal translocation. Your geneticist will offer to test other members of your family to find out whether your translocation is a new one or a family one.
What is the difference between homologous and non-homologous chromosomes?
Homologous chromosomes correspond to the chromosomes present on the same pair in contrast to non-homologous chromosomes where they are found on different pairs.
What does non reciprocal mean?
not moving alternately forward and backward. unanswered, unreciprocated, unrequited. not returned in kind. Antonyms: mutual, reciprocal. concerning each of two or more persons or things; especially given or done in return.