What is liquid-based cytology test?
Liquid-based cytology (LBC) is a new method of preparing cervical samples for cytological examination. Unlike the conventional ‘smear’ preparation, it involves making a suspension of cells from the sample and this is used to produce a thin layer of cells on a slide.
What is liquid-based cytology technique?
Liquid-based cytology is a technique that enables cells to be suspended in liquid medium and spread in monolayer and thus better morphological assessment is possible. It includes the preparation and evaluation of cells collected in a liquid fixative.
What is liquid-based Pap smear?
A Pap test can also show conditions that are not cancer, such as infection or inflammation. In a liquid-based Pap test, the cells are rinsed into a small container of liquid. The cells are then placed onto slides by a special machine and examined under a microscope to see if the cells are abnormal.
What is the difference between conventional and liquid-based Pap smear?
Conclusion This study indicates that liquid-based cytology does not perform better than conventional Pap tests in terms of relative sensitivity and PPV for detection of cervical cancer precursors. The conventional papanicolaou (Pap) test is considered suboptimal due to false-negative and false-positive test results.
Why is liquid based cytology done?
Liquid Based Cytology (LBC) is a new technique for collecting cytological samples in order to detect cervical cancer. With conventional cytology a smear taker takes a sample that is applied directly to a slide for microscopic investigation.
How do you collect samples for liquid based cytology?
Alternative collection method: A plastic spatula and cytobrush may also be used to collect LBC samples. Insert the spatula into the cervical os and rotate 360° with firm pressure. For SurePath: Snap off the head of the spatula (avoid touching the head of the device), and drop into the liquid vial (avoid splashing).
Why is the liquid based Pap test preferred?
Liquid-based Pap smears improve the diagnostic sensitivity of cervical cytology screening. They have the additional benefit of enabling easy testing for human papillomavirus (HPV). Thin Prep and SurePath are 2 methods currently approved by the FDA.
Why liquid-based cytology is done?
What is HPV positive?
Positive HPV test. A positive test result means that you have a type of high-risk HPV that’s linked to cervical cancer. It doesn’t mean that you have cervical cancer now, but it’s a warning sign that cervical cancer could develop in the future.
Is negative Pap smear good?
A normal (or “negative”) result means that no cell changes were found on your cervix. This is good news. But you still need to get Pap tests in the future. New cell changes can still form on your cervix.
How do you collect samples for liquid-based cytology?
What are the main advantages of moving from conventional cytology to liquid-based cytology?
Liquid-based cytology (LBC) has advantages of fewer unsatisfactory smears, faster and more efficient method, more accurate interpretation, less obscuring materials such as blood, mucous, inflammatory cells in smears and the use of residual cell suspension for testing human papillomavirus (HPV) DNA and …