What is DACOGEN drug used for?
This medication is used to treat a group of blood/bone marrow disorders (myelodysplastic syndromes-MDS) in which the bone marrow does not produce enough healthy blood cells. People with MDS may have problems such as infections, anemia, and easy bleeding/bruising.
Does DACOGEN work?
Overall anticancer responses were achieved in 17% of patients treated with decitabine, compared with 0% in patients treated with supportive care. Hematologic (blood) improvement occurred in 12% of patients treated with Dacogen, compared with 7% of patients treated with supportive care.
Is DACOGEN a chemotherapy drug?
Dacogen is the trade name for decitabine. In some cases, health care professionals may use the trade name Dacogen when referring to the generic drug name decitabine. Drug type: Decitibine is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
What is the cost of DACOGEN?
The cost for Dacogen intravenous powder for injection 50 mg is around $1,885 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
How is DACOGEN given?
Administer DACOGEN at a dose of 15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycles every 6 weeks upon hematologic recovery (ANC at least 1,000/µL and platelets at least 50,000/µL) for a minimum of 4 cycles. .
Does DACOGEN cause a cough?
easy bruising, unusual bleeding, purple or red spots under your skin; pale skin, cold hands and feet; or. cough with mucus, chest pain, feeling short of breath.
Does DACOGEN cause hair loss?
However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away: Hair loss. Constipation, diarrhea, stomach pain, upset stomach, throwing up, or feeling less hungry.
How long can you take DACOGEN?
Decitabine (Dacogen) Azacitidine can be injected under the skin or into a vein (IV), often for 7 days in a row, once a month.
What does decitabine treat?
Decitabine is used to treat myelodysplastic syndrome (a group of conditions in which the bone marrow produces blood cells that are misshapen and does not produce enough healthy blood cells). Decitabine is in a class of medications called hypomethylation agents.
Who manufactures decitabine?
About Dacogen® (decitabine) Dacogen® was developed by SuperGen, Inc., (now Astex Pharmaceuticals, Inc.) as a therapeutic agent for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) possessing cell differentiation-inducing activity through the inhibition of DNA methylation.
Is decitabine a chemo?
DECITABINE (dee SYE ta been) is a chemotherapy drug. This medicine reduces the growth of cancer cells.
How long does it take decitabine to work?
How long does it take for patients to respond to treatment? In the clinical study, the median time for patients to achieve some level of remission for either CR or CRh was 2 months (with a range of 0.8 to 4.2 months).