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What are the characteristic lab findings in chronic granulocytic leukemia?

What are the characteristic lab findings in chronic granulocytic leukemia?

The presence of the Ph chromosome in the bone marrow cells, along with a high white blood cell count and other characteristic blood and bone marrow test findings, confirm the diagnosis of CML. The bone marrow cells of about 95 percent of people with CML have a Ph chromosome that is detectable by cytogenetic analysis.

What is human chronic granulocytic leukemia?

Listen to pronunciation. (KRAH-nik GRAN-yoo-loh-SIH-tik loo-KEE-mee-uh) An indolent (slow-growing) cancer in which too many myeloblasts are found in the blood and bone marrow. Myeloblasts are a type of immature blood cell that makes white blood cells called myeloid cells.

What is smoldering chronic lymphocytic leukemia?

“Smouldering ” CLL concept: Patients with CLL in early stage (Binet’s stage A, Rai’s stage 0) who are not likely to progress and have a life-expectancy which is not different from that of sex- and age-matched controls, are considered as having “smouldering” CLL.

How is chronic granulocytic leukemia diagnosed?

Most people are diagnosed with CML through a blood test called a complete blood count (CBC) before they have any symptoms. A CBC counts the number of different kinds of cells in the blood. A CBC is often done as part of a regular medical checkup. People with CML have high levels of white blood cells.

Why is b12 elevated in CML?

In chronic lymphatic leukemia it is normal. In acute leukemia it is variable. 3. In chronic myeloid leukemia, the serum vitamim B12 exists in the bound form and the binding capacity for added B12 is increased.

Is chronic lymphocytic leukemia fatal?

CLL has a higher survival rate than many other cancers. The five-year survival rate is around 83 percent. This means that 83 percent of people with the condition are alive five years after diagnosis. However, in those over age 75, the five-year survival rate drops to less than 70 percent.

Is AML curable?

Although AML is a serious disease, it is treatable and often curable with chemotherapy with or without a bone marrow/stem cell transplant (see the Types of Treatment section). It is important to remember that statistics on the survival rates for people with AML are an estimate.